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Drugs and Chemotherapy



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Q1. Who developed a prodrug that depends on a viral enzyme to convert into its active form?

(a) Elion
(b) Watson
(c) Crick
(d) Pasteur

Q2. Which of the following agent targets ligand on virion?

(a) Protease inhibitor
(b) Disoxaril
(c) Tat inhibitor
(d) Zidovudine

Q3. Which of the following antibiotic is not involved in the inhibition of specific enzyme systems?

(a) Penicillin
(b) Tetracycline
(c) Sulphonamides
(d) Chloramphenicol

Q4. The antibiotic penicillin was discovered by which of the following researchers?

(a) Emmerich and Low
(b) Gratia and Dath
(c) Alexander Flemming
(d) Vuillemin

Q5. Which of the following chemothearpeutic agent is extensively used because of their antibacterial effectiveness in a wide range of bacterial infections?

(a) arsphenamine
(b) sulfanilamide
(c) sulfonamide
(d) sulfadiazine

Q6. Sulfonamides and arsphenamine are similar in their specificity for a special group of organism.

(a) True
(b) False
(c) -
(d) -

Q7. Sulfanilamide was synthesized by which of the following research scientists?

(a) Eisenberg
(b) Gelmo
(c) Ehrlich
(d) Domagk

Q8. Which was the first disease for which a chemotherapeutic agent was used?

(a) Syphilis
(b) Malaria
(c) Small pox
(d) AIDS

Q9. Phenol is considered as a chemotherapeutic agent.

(a) True
(b) False
(c) -
(d) -

Q10. Which of the following is not a characteristic of a chemotherapeutic agent?

(a) low toxicity for host cells
(b) high toxicity for the parasites
(c) less penetrating power
(d) does not affect the host?s natural defense mechanism


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